Sinovac: What do we know about China's Covid-19 vaccine?

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Sinovac: What do we know about China's Covid-19 vaccine?



As the global race to produce a Covid-19 vaccine continues, China appears to have made huge strides, with one of its vaccine front-runners,
Sinovac, already making its way abroad.


Shipments of Beijing-based biopharmaceutical company Sinovac's Covid-19 vaccine Coronavac have arrived in Indonesia in preparation for
a mass vaccination campaign, with another 1.8m doses due to arrive by January.

But the vaccine is yet to finish its late-stage trials, which begs the question: what exactly do we know about this Chinese vaccine?

What's the difference between Sinovac and some other vaccines?
CoronaVac is an inactivated vaccine, which works by using killed viral particles to expose the body's immune system to the virus without
risking a serious disease response.

The Moderna and Pfizer vaccines are mRNA vaccines - which means part of the coronavirus' genetic code is injected into the body,
triggering the body to begin making viral proteins, but not the whole virus, which is enough to train the immune system to attack.

"CoronaVac is a more traditional method [of vaccine] that is successfully used in many well known vaccines like rabies,"
Associate Prof Luo Dahai of the Nanyang Technological University told the BBC.

How effective is it?
It's hard to say at this point in time. According to scientific journal The Lancet, we currently only have information from the first and
second phase trials of CoronaVac.

Zhu Fengcai, one of the paper's authors, said those results - which are based on 144 participants in the phase one trial and 600 in
the phase two trial - meant the vaccine was "suitable for emergency use".

In September, Mr Yin of Sinovac said tests were performed on more than 1,000 volunteers, of which "some only showed minor fatigue
or discomfort… no more than 5%".

It began late-stage trials in Brazil - which has reported the second-highest death toll in the world - earlier in October. These trials were
briefly halted in November after the reported death of a volunteer, but resumed after the death was found to have no links to
the vaccine.

How many doses can they produce a year?
Sinovac will be able to produce 300 million doses a year in its newly built 20,000 sqm production plant, its chairman told state media
outlet CGTN.

Like all the other vaccines, it requires two doses, which means it is currently only able to inoculate 150m people a year - just over
a tenth of China's population.

However, it has already delivered doses to Indonesia, and Sinovac has secured other deals with Turkey, Brazil and Chile.

Analysts point to China's bid to win the vaccine diplomacy race, which has also reportedly seen China's President Xi Jinping pledged to
set aside $2bn for the African continent, while also offering Latin American and Caribbean countries a $1bn loan to buy vaccines.
It's unclear what the terms of such a deal might be.

Read the full news here. : slotxo

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